3ibw: Difference between revisions

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{{STRUCTURE_3ibw|  PDB=3ibw  |  SCENE=  }}
==Crystal Structure of the ACT domain from GTP pyrophosphokinase of Chlorobium tepidum. Northeast Structural Genomics Consortium Target CtR148A==
===Crystal Structure of the ACT domain from GTP pyrophosphokinase of Chlorobium tepidum. Northeast Structural Genomics Consortium Target CtR148A===
<StructureSection load='3ibw' size='340' side='right' caption='[[3ibw]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[3ibw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chlorobaculum_tepidum Chlorobaculum tepidum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IBW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IBW FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/Q8KC80_CHLTE Q8KC80_CHLTE]] In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity).[RuleBase:RU003847]
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
 
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CT1545, relA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1097 Chlorobaculum tepidum])</td></tr>
==About this Structure==
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/GTP_diphosphokinase GTP diphosphokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.6.5 2.7.6.5] </span></td></tr>
[[3ibw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chlorobaculum_tepidum Chlorobaculum tepidum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IBW OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ibw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ibw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ibw RCSB], [http://www.ebi.ac.uk/pdbsum/3ibw PDBsum]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ib/3ibw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Chlorobaculum tepidum]]
[[Category: Chlorobaculum tepidum]]
[[Category: GTP diphosphokinase]]
[[Category: GTP diphosphokinase]]
[[Category: Acton, T B.]]
[[Category: Acton, T B]]
[[Category: Ciccosanti,C.]]
[[Category: Ciccosanti,C]]
[[Category: Everett, J K.]]
[[Category: Everett, J K]]
[[Category: Hunt,J F.]]
[[Category: Hunt,J F]]
[[Category: Janjua,J.]]
[[Category: Janjua,J]]
[[Category: Montelione, G T.]]
[[Category: Montelione, G T]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Structural genomic]]
[[Category: Nair, R.]]
[[Category: Nair, R]]
[[Category: Rost, B.]]
[[Category: Rost, B]]
[[Category: Seetharaman, J.]]
[[Category: Seetharaman, J]]
[[Category: Su, M.]]
[[Category: Su, M]]
[[Category: Tong,L.]]
[[Category: Tong,L]]
[[Category: Vorobiev, S.]]
[[Category: Vorobiev, S]]
[[Category: Wang,H.]]
[[Category: Wang,H]]
[[Category: Xiao,R.]]
[[Category: Xiao,R]]
[[Category: Act domain]]
[[Category: Act domain]]
[[Category: Ctr148a]]
[[Category: Ctr148a]]
Line 29: Line 42:
[[Category: Kinase]]
[[Category: Kinase]]
[[Category: Nesg]]
[[Category: Nesg]]
[[Category: Northeast structural genomics consortium]]
[[Category: PSI, Protein structure initiative]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Structural genomic]]
[[Category: Transferase]]
[[Category: Transferase]]
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