4jwn: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

===Ternary complex of D256A mutant of DNA Polymerase Beta===

~~The entry 4jwn is ON HOLD~~

==Function==

[[http://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN]] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>

~~Authors~~: ~~Batra, V~~.K.~~, Perera, L~~.~~, Ping, L., Shock, D.D., Beard, W.A., Pedersen, L.C., Pedersen, L~~.G.~~, Wilson, S~~.H.

==About this Structure==

[[4jwn]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JWN OCA].

~~Description~~: ~~Ternary~~ complex ~~of D256A mutant of DNA Polymerase Beta~~

==Reference==

[[Category: DNA-directed DNA polymerase]]

[[Category: Homo sapiens]]

[[Category: Batra, V K.]]

[[Category: Beard, W A.]]

[[Category: Pedersen, L C.]]

[[Category: Pedersen, L G.]]

[[Category: Perera, L.]]

[[Category: Ping, L.]]

[[Category: Shock, D D.]]

[[Category: Wilson, S H.]]

[[Category: Dntp]]

[[Category: Non-hydrolyzable analog]]

[[Category: Nucleotidyl transfer]]

[[Category: Transferase-dna complex]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4jwn|  PDB=4jwn  |  SCENE=  }}
+===Ternary complex of D256A mutant of DNA Polymerase Beta===
+{{ABSTRACT_PUBMED_23647366}}
-The entry 4jwn is ON HOLD
+==Function==
+[[http://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN]] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>
-Authors: Batra, V.K., Perera, L., Ping, L., Shock, D.D., Beard, W.A., Pedersen, L.C., Pedersen, L.G., Wilson, S.H.
+==About this Structure==
+[[4jwn]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JWN OCA].
-Description: Ternary complex of D256A mutant of DNA Polymerase Beta
+==Reference==
+<ref group="xtra">PMID:023647366</ref><references group="xtra"/><references/>
+[[Category: DNA-directed DNA polymerase]]
+[[Category: Homo sapiens]]
+[[Category: Batra, V K.]]
+[[Category: Beard, W A.]]
+[[Category: Pedersen, L C.]]
+[[Category: Pedersen, L G.]]
+[[Category: Perera, L.]]
+[[Category: Ping, L.]]
+[[Category: Shock, D D.]]
+[[Category: Wilson, S H.]]
+[[Category: Dntp]]
+[[Category: Non-hydrolyzable analog]]
+[[Category: Nucleotidyl transfer]]
+[[Category: Transferase-dna complex]]