3l1l: Difference between revisions
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Revision as of 19:58, 4 April 2013
Structure of Arg-bound Escherichia coli AdiC
Template:ABSTRACT PUBMED 20090677
Function
[ADIC_ECO57] Major component of the acid-resistance (AR) system allowing enteric pathogens to survive the acidic environment in the stomach. Exchanges extracellular arginine for its intracellular decarboxylation product agmatine (Agm) thereby expelling intracellular protons.
About this Structure
3l1l is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Gao X, Zhou L, Jiao X, Lu F, Yan C, Zeng X, Wang J, Shi Y. Mechanism of substrate recognition and transport by an amino acid antiporter. Nature. 2010 Feb 11;463(7282):828-32. Epub 2010 Jan 20. PMID:20090677 doi:10.1038/nature08741