2eau: Difference between revisions

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[[Image:2eau.gif|left|200px]]<br /><applet load="2eau" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2eau.gif|left|200px]]
caption="2eau, resolution 2.80&Aring;" />
 
'''Crystal structure of the SR CA2+-ATPASE with bound CPA in the presence of curcumin'''<br />
{{Structure
|PDB= 2eau |SIZE=350|CAPTION= <scene name='initialview01'>2eau</scene>, resolution 2.80&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CZA:(6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE'>CZA</scene> and <scene name='pdbligand=PTY:PHOSPHATIDYLETHANOLAMINE'>PTY</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Calcium-transporting_ATPase Calcium-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.8 3.6.3.8]
|GENE=
}}
 
'''Crystal structure of the SR CA2+-ATPASE with bound CPA in the presence of curcumin'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2EAU is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus] with <scene name='pdbligand=CZA:'>CZA</scene> and <scene name='pdbligand=PTY:'>PTY</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Calcium-transporting_ATPase Calcium-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.8 3.6.3.8] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EAU OCA].  
2EAU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EAU OCA].  


==Reference==
==Reference==
Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors., Takahashi M, Kondou Y, Toyoshima C, Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5800-5. Epub 2007 Mar 26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17389383 17389383]
Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors., Takahashi M, Kondou Y, Toyoshima C, Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5800-5. Epub 2007 Mar 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17389383 17389383]
[[Category: Calcium-transporting ATPase]]
[[Category: Calcium-transporting ATPase]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
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[[Category: p-type atpase]]
[[Category: p-type atpase]]


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