4i90: Difference between revisions
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{{STRUCTURE_4i90| PDB=4i90 | SCENE= }} | {{STRUCTURE_4i90| PDB=4i90 | SCENE= }} | ||
===Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from S. aureus bound to choline=== | ===Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from S. aureus bound to choline=== | ||
{{ABSTRACT_PUBMED_23576432}} | |||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4i90]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_str._newman Staphylococcus aureus subsp. aureus str. newman]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I90 OCA]. | [[4i90]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_str._newman Staphylococcus aureus subsp. aureus str. newman]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I90 OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:023576432</ref><references group="xtra"/><references/> | |||
[[Category: Phosphatidylinositol diacylglycerol-lyase]] | [[Category: Phosphatidylinositol diacylglycerol-lyase]] | ||
[[Category: Staphylococcus aureus subsp. aureus str. newman]] | [[Category: Staphylococcus aureus subsp. aureus str. newman]] | ||
Revision as of 05:06, 23 October 2013
Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from S. aureus bound to choline
Template:ABSTRACT PUBMED 23576432
Function
[PLC_STAAE] Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Potential virulence factor.
About this Structure
4i90 is a 1 chain structure with sequence from Staphylococcus aureus subsp. aureus str. newman. Full crystallographic information is available from OCA.
Reference
- Cheng J, Goldstein R, Gershenson A, Stec B, Roberts MF. The cation-pi box is a specific phosphatidylcholine membrane targeting motif. J Biol Chem. 2013 May 24;288(21):14863-73. doi: 10.1074/jbc.M113.466532. Epub, 2013 Apr 10. PMID:23576432 doi:https://dx.doi.org/10.1074/jbc.M113.466532
