3mcq: Difference between revisions

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~~{{STRUCTURE_3mcq| PDB=3mcq | SCENE= }}~~

==Crystal structure of Thiamine-monophosphate kinase (Mfla_0573) from METHYLOBACILLUS FLAGELLATUS KT at 1.91 A resolution==

===Crystal structure of Thiamine-monophosphate kinase (Mfla_0573) from METHYLOBACILLUS FLAGELLATUS KT at 1.91 A resolution===

== Structural highlights ==

==~~Function~~==

<table><tr><td colspan='2'>[[3mcq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methylobacillus_flagellatus Methylobacillus flagellatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MCQ FirstGlance]. <br>

[[~~http://www.uniprot.org/uniprot/Q1H3U4_METFK Q1H3U4_METFK~~]] ~~Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP)~~, ~~the active form of vitamin B1 (By similarity).~~[~~HAMAP-Rule:MF_02128~~]

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>

<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>

==~~About this Structure~~==

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mfla_0573 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=405 Methylobacillus flagellatus])</td></tr>

[[3mcq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methylobacillus_flagellatus Methylobacillus flagellatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCQ OCA].

<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thiamine-phosphate_kinase Thiamine-phosphate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.16 2.7.4.16] </span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mcq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mcq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mcq RCSB], [http://www.ebi.ac.uk/pdbsum/3mcq PDBsum]</span></td></tr>

</table>

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

Check<jmol>

<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mc/3mcq_consurf.spt"</scriptWhenChecked>

<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>

<text>to colour the structure by Evolutionary Conservation</text>

</jmolCheckbox>

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].

__TOC__

</StructureSection>

[[Category: Methylobacillus flagellatus]]

[[Category: Thiamine-phosphate kinase]]

[[Category: ~~JCSG, Joint Center for~~ Structural ~~Genomics.~~]]

[[Category: Structural genomic]]

[[Category: Jcsg]]

[[Category: ~~Joint center for structural genomic]]~~

[[Category: PSI, Protein structure initiative]]

~~[[Category:~~ Protein structure initiative]]

~~[[Category: Psi-2]]~~

~~[[Category: Structural genomic~~]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_3mcq|  PDB=3mcq  |  SCENE=  }}
+==Crystal structure of Thiamine-monophosphate kinase (Mfla_0573) from METHYLOBACILLUS FLAGELLATUS KT at 1.91 A resolution==
-===Crystal structure of Thiamine-monophosphate kinase (Mfla_0573) from METHYLOBACILLUS FLAGELLATUS KT at 1.91 A resolution===
+<StructureSection load='3mcq' size='340' side='right' caption='[[3mcq]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
+== Structural highlights ==
-==Function==
+<table><tr><td colspan='2'>[[3mcq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methylobacillus_flagellatus Methylobacillus flagellatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MCQ FirstGlance]. <br>
-[[http://www.uniprot.org/uniprot/Q1H3U4_METFK Q1H3U4_METFK]] Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity).[HAMAP-Rule:MF_02128]
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-==About this Structure==
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mfla_0573 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=405 Methylobacillus flagellatus])</td></tr>
-[[3mcq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methylobacillus_flagellatus Methylobacillus flagellatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCQ OCA].
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thiamine-phosphate_kinase Thiamine-phosphate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.16 2.7.4.16] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mcq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mcq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mcq RCSB], [http://www.ebi.ac.uk/pdbsum/3mcq PDBsum]</span></td></tr>
+</table>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mc/3mcq_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
 [[Category: Methylobacillus flagellatus]]
 [[Category: Thiamine-phosphate kinase]]
-[[Category: JCSG, Joint Center for Structural Genomics.]]
+[[Category: Structural genomic]]
 [[Category: Jcsg]]
-[[Category: Joint center for structural genomic]]
+[[Category: PSI, Protein structure initiative]]
-[[Category: Protein structure initiative]]
-[[Category: Psi-2]]
-[[Category: Structural genomic]]
 [[Category: Transferase]]