3m45: Difference between revisions
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Revision as of 23:25, 10 April 2013
Crystal structure of Ig1 domain of mouse SynCAM 2
Template:ABSTRACT PUBMED 20739279
Function
[CADM2_MOUSE] Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes (By similarity).
About this Structure
3m45 is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Fogel AI, Li Y, Giza J, Wang Q, Lam TT, Modis Y, Biederer T. N-glycosylation at the SynCAM immunoglobulin interface modulates synaptic adhesion. J Biol Chem. 2010 Aug 25. PMID:20739279 doi:10.1074/jbc.M110.120865
