4e1k: Difference between revisions
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{{STRUCTURE_4e1k| PDB=4e1k | SCENE= }} | |||
===GlmU in complex with a Quinazoline Compound=== | |||
{{ABSTRACT_PUBMED_22721802}} | |||
The | ==Function== | ||
[[http://www.uniprot.org/uniprot/GLMU_HAEIN GLMU_HAEIN]] Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.<ref>PMID:18029420</ref> | |||
==About this Structure== | |||
[[4e1k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae_rd_kw20 Haemophilus influenzae rd kw20]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E1K OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:022721802</ref><references group="xtra"/><references/> | |||
[[Category: Haemophilus influenzae rd kw20]] | |||
[[Category: Doig, P.]] | |||
[[Category: Larsen, N A.]] | |||
[[Category: Acyltransferase]] | |||
[[Category: Cell shape]] | |||
[[Category: Cell wall biogenesis/degradation]] | |||
[[Category: Metal-binding]] | |||
[[Category: Multifunctional enzyme]] | |||
[[Category: Nucleotidyl transferase]] | |||
[[Category: Peptidoglycan synthesis]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||
[[Category: Uridyltransferase]] | |||