4iia: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4iia|  PDB=4iia  |  SCENE=  }}
===Low resolution crystal structure of the NTF2-like domain of human G3BP1===
{{ABSTRACT_PUBMED_24324649}}


The entry 4iia is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/G3BP1_HUMAN G3BP1_HUMAN]] May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.<ref>PMID:9889278</ref> <ref>PMID:11604510</ref>  


Authors: Vognsen, T., Moeller, I.R., Kristensen, O.
==About this Structure==
[[4iia]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IIA OCA].  


Description: Low resolution crystal structure of the NTF2-like domain of human G3BP1
==Reference==
<ref group="xtra">PMID:024324649</ref><references group="xtra"/><references/>
[[Category: Kristensen, O.]]
[[Category: Moeller, I R.]]
[[Category: Vognsen, T.]]
[[Category: Hydrolase]]
[[Category: Ntf2-like domain]]
Retrieved from "https://proteopedia.org/4iia"