4jbs: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4jbs|  PDB=4jbs  |  SCENE=  }}
===Crystal structure of the human Endoplasmic Reticulum Aminopeptidase 2 in complex with PHOSPHINIC PSEUDOTRIPEPTIDE inhibitor.===
{{ABSTRACT_PUBMED_24248368}}


The entry 4jbs is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/ERAP2_HUMAN ERAP2_HUMAN]] Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys.<ref>PMID:12799365</ref> <ref>PMID:15908954</ref> <ref>PMID:16286653</ref>  


Authors: Saridakis, E., Birtley, J., Stratikos, E., Mavridis, I.M.
==About this Structure==
[[4jbs]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JBS OCA].  


Description:
==Reference==
<ref group="xtra">PMID:024248368</ref><references group="xtra"/><references/>
[[Category: Birtley, J.]]
[[Category: Mavridis, I M.]]
[[Category: Saridakis, E.]]
[[Category: Stratikos, E.]]
[[Category: Aminopeptidase]]
[[Category: Endoplasmic reticulum]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Thermolysin-like catalytic domain]]
[[Category: Zinc binding]]
Retrieved from "https://proteopedia.org/4jbs"