4jj8: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4jj8|  PDB=4jj8  |  SCENE=  }}
===Caspase-3 specific unnatural amino acid peptides===
{{ABSTRACT_PUBMED_23614665}}


The entry 4jj8 is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/CASP7_HUMAN CASP7_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.


Authors: Vickers, C.J., Gonzalez-Paez, G.E., Wolan, D.W.
==About this Structure==
[[4jj8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JJ8 OCA].  


Description: Caspase-3 specific unnatural amino acid peptides
==Reference==
<ref group="xtra">PMID:023614665</ref><references group="xtra"/><references/>
[[Category: Caspase-7]]
[[Category: Homo sapiens]]
[[Category: Gonzalez-Paez, G E.]]
[[Category: Vickers, C J.]]
[[Category: Wolan, D W.]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Protease]]