4jj8: Difference between revisions
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{{STRUCTURE_4jj8| PDB=4jj8 | SCENE= }} | |||
===Caspase-3 specific unnatural amino acid peptides=== | |||
{{ABSTRACT_PUBMED_23614665}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CASP7_HUMAN CASP7_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death. | |||
==About this Structure== | |||
[[4jj8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JJ8 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023614665</ref><references group="xtra"/><references/> | |||
[[Category: Caspase-7]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Gonzalez-Paez, G E.]] | |||
[[Category: Vickers, C J.]] | |||
[[Category: Wolan, D W.]] | |||
[[Category: Hydrolase-hydrolase inhibitor complex]] | |||
[[Category: Protease]] | |||