4jmo: Difference between revisions
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{{STRUCTURE_4jmo| PDB=4jmo | SCENE= }} | |||
===Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)-4-methoxybenzenesulfonamide=== | |||
{{ABSTRACT_PUBMED_24112024}} | |||
The | ==Function== | ||
[[http://www.uniprot.org/uniprot/CYH2_HUMAN CYH2_HUMAN]] Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane.<ref>PMID:17398095</ref> | |||
==About this Structure== | |||
[[4jmo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JMO OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024112024</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Hoh, F.]] | |||
[[Category: Arf1]] | |||
[[Category: Nucleotide exchange factor]] | |||
[[Category: Signaling protein-inhibitor complex]] | |||