4jqu: Difference between revisions

Line 1:

~~'''Unreleased~~ structure~~'''~~

===Crystal structure of Ubc7p in complex with the U7BR of Cue1p===

~~The entry 4jqu~~ is ~~ON HOLD~~ ~~until Paper Publication~~

==Function==

[[http://www.uniprot.org/uniprot/UBC7_YEAST UBC7_YEAST]] Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in degradation of misfolded or regulated proteins localized in the endoplasmic reticulum (ER) lumen or membrane via the ubiquitin-proteasome system. Cognate E2 conjugating enzyme for the DOA10 ubiquitin ligase complex, which is part of the ERAD-C pathway responsible for the rapid degradation of membrane proteins with misfolded cytoplasmic domains, and of the HRD1 ubiquitin ligase complex, which is part of the ERAD-L and ERAD-M pathways responsible for the rapid degradation of soluble lumenal and membrane proteins with misfolded lumenal domains (ERAD-L), or ER-membrane proteins with misfolded transmembrane domains (ERAD-M). Involved in resistance to cadmium poisoning.<ref>PMID:8393731</ref> <ref>PMID:9388185</ref> <ref>PMID:9695950</ref> <ref>PMID:11641273</ref> <ref>PMID:11390656</ref> <ref>PMID:11146622</ref> <ref>PMID:16873066</ref>

~~Authors~~: ~~Liang, Y~~.-H.~~, Metzger, M~~.B.~~, Weissman, A~~.M.~~, Ji, X~~.

==About this Structure==

[[4jqu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JQU OCA].

~~Description~~: ~~Crystal structure of~~ Ubc7p in complex ~~with the U7BR of Cue1p~~

==Reference==

[[Category: Saccharomyces cerevisiae s288c]]

[[Category: Ubiquitin--protein ligase]]

[[Category: Ji, X.]]

[[Category: Liang, Y H.]]

[[Category: Metzger, M B.]]

[[Category: Weissman, A M.]]

[[Category: Ligase-activator complex]]

[[Category: Ligase-protein binding complex]]

[[Category: Ubc7p:u7br complex]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4jqu|  PDB=4jqu  |  SCENE=  }}
+===Crystal structure of Ubc7p in complex with the U7BR of Cue1p===
+{{ABSTRACT_PUBMED_23665230}}
-The entry 4jqu is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/UBC7_YEAST UBC7_YEAST]] Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in degradation of misfolded or regulated proteins localized in the endoplasmic reticulum (ER) lumen or membrane via the ubiquitin-proteasome system. Cognate E2 conjugating enzyme for the DOA10 ubiquitin ligase complex, which is part of the ERAD-C pathway responsible for the rapid degradation of membrane proteins with misfolded cytoplasmic domains, and of the HRD1 ubiquitin ligase complex, which is part of the ERAD-L and ERAD-M pathways responsible for the rapid degradation of soluble lumenal and membrane proteins with misfolded lumenal domains (ERAD-L), or ER-membrane proteins with misfolded transmembrane domains (ERAD-M). Involved in resistance to cadmium poisoning.<ref>PMID:8393731</ref> <ref>PMID:9388185</ref> <ref>PMID:9695950</ref> <ref>PMID:11641273</ref> <ref>PMID:11390656</ref> <ref>PMID:11146622</ref> <ref>PMID:16873066</ref>
-Authors: Liang, Y.-H., Metzger, M.B., Weissman, A.M., Ji, X.
+==About this Structure==
+[[4jqu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JQU OCA].
-Description: Crystal structure of Ubc7p in complex with the U7BR of Cue1p
+==Reference==
+<ref group="xtra">PMID:023665230</ref><references group="xtra"/><references/>
+[[Category: Saccharomyces cerevisiae s288c]]
+[[Category: Ubiquitin--protein ligase]]
+[[Category: Ji, X.]]
+[[Category: Liang, Y H.]]
+[[Category: Metzger, M B.]]
+[[Category: Weissman, A M.]]
+[[Category: Ligase-activator complex]]
+[[Category: Ligase-protein binding complex]]
+[[Category: Ubc7p:u7br complex]]