4jr2: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_4jr2|  PDB=4jr2  |  SCENE=  }}
+===Human procaspase-7/caspase-7 heterodimer bound to Ac-DEVD-CMK===
-The entry 4jr2 is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/CASP7_HUMAN CASP7_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.
-Authors: Thomsen, N.D., Wells, J.A.
+==About this Structure==
+[[4jr2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JR2 OCA].
-Description:
+[[Category: Caspase-7]]
+[[Category: Homo sapiens]]
+[[Category: Thomsen, N D.]]
+[[Category: Wells, J A.]]
+[[Category: Activity based probe]]
+[[Category: Apoptosis]]
+[[Category: Caspase]]
+[[Category: Hydrolase-hydrolase inhibitor complex]]
+[[Category: Irreversible inhibitor]]
+[[Category: Proenzyme]]
+[[Category: Protease]]
+[[Category: Protein-peptide complex]]

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