4jsm: Difference between revisions
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{{STRUCTURE_4jsm| PDB=4jsm | SCENE= }} | |||
===Structure of bovine endothelial nitric oxide synthase heme domain in complex with 6-(((5-(((3-fluorophenethyl)amino)methyl)pyridin-3-yl)oxy)methyl)-4-methylpyridin-2-amine=== | |||
{{ABSTRACT_PUBMED_23867386}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/NOS3_BOVIN NOS3_BOVIN]] Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. | |||
==About this Structure== | |||
[[4jsm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JSM OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023867386</ref><references group="xtra"/><references/> | |||
[[Category: Bos taurus]] | |||
[[Category: Li, H.]] | |||
[[Category: Poulos, T L.]] | |||
[[Category: Nitric oxide synthase]] | |||
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | |||