4jsm: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4jsm|  PDB=4jsm  |  SCENE=  }}
===Structure of bovine endothelial nitric oxide synthase heme domain in complex with 6-(((5-(((3-fluorophenethyl)amino)methyl)pyridin-3-yl)oxy)methyl)-4-methylpyridin-2-amine===
{{ABSTRACT_PUBMED_23867386}}


The entry 4jsm is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/NOS3_BOVIN NOS3_BOVIN]] Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.


Authors: Li, H., Poulos, T.L.
==About this Structure==
[[4jsm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JSM OCA].  


Description: Structure of bovine endothelial nitric oxide synthase heme domain in complex with 6-(((5-(((3-fluorophenethyl)amino)methyl)pyridin-3-yl)oxy)methyl)-4-methylpyridin-2-amine
==Reference==
<ref group="xtra">PMID:023867386</ref><references group="xtra"/><references/>
[[Category: Bos taurus]]
[[Category: Li, H.]]
[[Category: Poulos, T L.]]
[[Category: Nitric oxide synthase]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]