4k00: Difference between revisions
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{{STRUCTURE_4k00| PDB=4k00 | SCENE= }} | {{STRUCTURE_4k00| PDB=4k00 | SCENE= }} | ||
===Crystal structure of Slr0204, a 1,4-dihydroxy-2-naphthoyl-CoA thioesterase from Synechocystis=== | ===Crystal structure of Slr0204, a 1,4-dihydroxy-2-naphthoyl-CoA thioesterase from Synechocystis=== | ||
{{ABSTRACT_PUBMED_24100308}} | |||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4k00]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[4k00]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Syny3 Syny3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K00 OCA]. | ||
==Reference== | ==Reference== | ||
<references group="xtra"/><references/> | <ref group="xtra">PMID:024100308</ref><references group="xtra"/><references/> | ||
[[Category: 1,4-dihydroxy-2-naphthoyl-CoA hydrolase]] | [[Category: 1,4-dihydroxy-2-naphthoyl-CoA hydrolase]] | ||
[[Category: | [[Category: Syny3]] | ||
[[Category: Allen, W J.]] | [[Category: Allen, W J.]] | ||
[[Category: Basset, G.]] | [[Category: Basset, G.]] | ||
Revision as of 07:02, 15 January 2014
Crystal structure of Slr0204, a 1,4-dihydroxy-2-naphthoyl-CoA thioesterase from Synechocystis
Template:ABSTRACT PUBMED 24100308
Function
[DNCH_SYNY3] Catalyzes the specific hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis. Is not active on benzoyl-CoA, phenylacetyl-CoA and aliphatic acyl-CoA thioesters.[1]
About this Structure
4k00 is a 2 chain structure with sequence from Syny3. Full crystallographic information is available from OCA.
Reference
- Furt F, Allen WJ, Widhalm JR, Madzelan P, Rizzo RC, Basset G, Wilson MA. Functional convergence of structurally distinct thioesterases from cyanobacteria and plants involved in phylloquinone biosynthesis. Acta Crystallogr D Biol Crystallogr. 2013 Oct;69(Pt 10):1876-88. doi:, 10.1107/S0907444913015771. Epub 2013 Sep 20. PMID:24100308 doi:https://dx.doi.org/10.1107/S0907444913015771
- ↑ Widhalm JR, van Oostende C, Furt F, Basset GJ. A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1. Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5599-603. doi:, 10.1073/pnas.0900738106. Epub 2009 Mar 25. PMID:19321747 doi:10.1073/pnas.0900738106
