2et0: Difference between revisions

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[[Image:2et0.gif|left|200px]]<br /><applet load="2et0" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2et0.gif|left|200px]]
caption="2et0, resolution 1.7&Aring;" />
 
'''The structure of a three-way DNA junction in complex with a metallo-supramolecular helicate reveals a new target for drugs'''<br />
{{Structure
|PDB= 2et0 |SIZE=350|CAPTION= <scene name='initialview01'>2et0</scene>, resolution 1.7&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene> and <scene name='pdbligand=NPM:N-[(1E)-PYRIDIN-2-YLMETHYLENE]-N-[4-(4-{[(1E)-PYRIDIN-2-YLMETHYLENE]AMINO}BENZYL)PHENYL]AMINE'>NPM</scene>
|ACTIVITY=
|GENE=
}}
 
'''The structure of a three-way DNA junction in complex with a metallo-supramolecular helicate reveals a new target for drugs'''
 


==About this Structure==
==About this Structure==
2ET0 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=FE2:'>FE2</scene> and <scene name='pdbligand=NPM:'>NPM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ET0 OCA].  
2ET0 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ET0 OCA].  


==Reference==
==Reference==
Molecular recognition of a three-way DNA junction by a metallosupramolecular helicate., Oleksy A, Blanco AG, Boer R, Uson I, Aymami J, Rodger A, Hannon MJ, Coll M, Angew Chem Int Ed Engl. 2006 Feb 13;45(8):1227-31. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16463312 16463312]
Molecular recognition of a three-way DNA junction by a metallosupramolecular helicate., Oleksy A, Blanco AG, Boer R, Uson I, Aymami J, Rodger A, Hannon MJ, Coll M, Angew Chem Int Ed Engl. 2006 Feb 13;45(8):1227-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16463312 16463312]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Aymami, J.]]
[[Category: Aymami, J.]]
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[[Category: drug-dna complex]]
[[Category: drug-dna complex]]


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