2eu0: Difference between revisions

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[[Image:2eu0.gif|left|200px]]<br /><applet load="2eu0" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2eu0.gif|left|200px]]
caption="2eu0" />
 
'''The NMR ensemble structure of the Itk SH2 domain bound to a phosphopeptide'''<br />
{{Structure
|PDB= 2eu0 |SIZE=350|CAPTION= <scene name='initialview01'>2eu0</scene>
|SITE=
|LIGAND= <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene> and <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2]
|GENE= Itk, Emt, Tlk, Tsk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
}}
 
'''The NMR ensemble structure of the Itk SH2 domain bound to a phosphopeptide'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2EU0 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=ACE:'>ACE</scene> and <scene name='pdbligand=NH2:'>NH2</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EU0 OCA].  
2EU0 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EU0 OCA].  


==Reference==
==Reference==
Molecular details of Itk activation by prolyl isomerization and phospholigand binding: the NMR structure of the Itk SH2 domain bound to a phosphopeptide., Pletneva EV, Sundd M, Fulton DB, Andreotti AH, J Mol Biol. 2006 Mar 24;357(2):550-61. Epub 2006 Jan 18. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16436281 16436281]
Molecular details of Itk activation by prolyl isomerization and phospholigand binding: the NMR structure of the Itk SH2 domain bound to a phosphopeptide., Pletneva EV, Sundd M, Fulton DB, Andreotti AH, J Mol Biol. 2006 Mar 24;357(2):550-61. Epub 2006 Jan 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16436281 16436281]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: tsk]]
[[Category: tsk]]


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