2ew5: Difference between revisions

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[[Image:2ew5.gif|left|200px]]<br /><applet load="2ew5" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ew5.gif|left|200px]]
caption="2ew5, resolution 2.2&Aring;" />
 
'''Structure of Helicobacter Pylori peptide deformylase in complex with inhibitor'''<br />
{{Structure
|PDB= 2ew5 |SIZE=350|CAPTION= <scene name='initialview01'>2ew5</scene>, resolution 2.2&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene> and <scene name='pdbligand=Y12:4-{(1E)-3-OXO-3-[(2-PHENYLETHYL)AMINO]PROP-1-EN-1-YL}-1,2-PHENYLENE DIACETATE'>Y12</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88]
|GENE=
}}
 
'''Structure of Helicobacter Pylori peptide deformylase in complex with inhibitor'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2EW5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori] with <scene name='pdbligand=CO:'>CO</scene> and <scene name='pdbligand=Y12:'>Y12</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EW5 OCA].  
2EW5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EW5 OCA].  


==Reference==
==Reference==
Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: reverse docking, enzymatic assay, and X-ray crystallography validation., Cai J, Han C, Hu T, Zhang J, Wu D, Wang F, Liu Y, Ding J, Chen K, Yue J, Shen X, Jiang H, Protein Sci. 2006 Sep;15(9):2071-81. Epub 2006 Aug 1. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16882991 16882991]
Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: reverse docking, enzymatic assay, and X-ray crystallography validation., Cai J, Han C, Hu T, Zhang J, Wu D, Wang F, Liu Y, Ding J, Chen K, Yue J, Shen X, Jiang H, Protein Sci. 2006 Sep;15(9):2071-81. Epub 2006 Aug 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16882991 16882991]
[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
[[Category: Peptide deformylase]]
[[Category: Peptide deformylase]]
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[[Category: inhibitor]]
[[Category: inhibitor]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:15:09 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:45:07 2008''
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