2ewn: Difference between revisions

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[[Image:2ewn.gif|left|200px]]<br /><applet load="2ewn" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ewn.gif|left|200px]]
caption="2ewn, resolution 2.80&Aring;" />
 
'''Ecoli Biotin Repressor with co-repressor analog'''<br />
{{Structure
|PDB= 2ewn |SIZE=350|CAPTION= <scene name='initialview01'>2ewn</scene>, resolution 2.80&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=BTX:((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE'>BTX</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Biotin--[acetyl-CoA-carboxylase]_ligase Biotin--[acetyl-CoA-carboxylase] ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.15 6.3.4.15]
|GENE= birA, bioR, dhbB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''Ecoli Biotin Repressor with co-repressor analog'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2EWN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=BTX:'>BTX</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Biotin--[acetyl-CoA-carboxylase]_ligase Biotin--[acetyl-CoA-carboxylase] ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.15 6.3.4.15] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWN OCA].  
2EWN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWN OCA].  


==Reference==
==Reference==
Co-repressor induced order and biotin repressor dimerization: a case for divergent followed by convergent evolution., Wood ZA, Weaver LH, Brown PH, Beckett D, Matthews BW, J Mol Biol. 2006 Mar 24;357(2):509-23. Epub 2006 Jan 6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16438984 16438984]
Co-repressor induced order and biotin repressor dimerization: a case for divergent followed by convergent evolution., Wood ZA, Weaver LH, Brown PH, Beckett D, Matthews BW, J Mol Biol. 2006 Mar 24;357(2):509-23. Epub 2006 Jan 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16438984 16438984]
[[Category: Biotin--[acetyl-CoA-carboxylase] ligase]]
[[Category: Biotin--[acetyl-CoA-carboxylase] ligase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: helix-turn-helix]]
[[Category: helix-turn-helix]]


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