Sandbox Reserved 592: Difference between revisions
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== Function == | == Function == | ||
There are two types of histone methyltransferases: lysine specific and argine specific; each are residues which the enzyme transfers a mathyl group to. Within the lysine specific, there are further two main types: SET (Su(var)3-9, Enhancer of Zeste, Trithorax) and non-SET domains. These domains are an essential part of the enzyme because the main | There are two types of histone methyltransferases: lysine specific and argine specific; each are residues which the enzyme transfers a mathyl group to. Within the lysine specific, there are further two main types: SET (Su(var)3-9, Enhancer of Zeste, Trithorax) and non-SET domains. These domains are an essential part of the enzyme because the main catalytic occurs in SET domain of the methyltransferase. SUV39h1 is considered to have a lysine specific SET domain which catalyzes the methyltransferase. In the nucleosomes, there are four different proteins; each consists of two copies which make the entire nucleosome. The mechanism by which SUV39H1 methylates the histone pro | ||
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== Clinical relevence == | == Clinical relevence == | ||
