Sandbox Reserved 592: Difference between revisions
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SUV39h1 is part of a class of enzymes that deals with the methyltransferase of histone proteins in nucleosomes. The methylation of histone proteins is an essential part of an area of genetics which deals with the modification of histone proteins called epigenomics. Epigenomics is the study of modifications of nucleosomes, which inhibit or express gene trancriscription without changing the underlining DNA sequence. Methylation of histone protein is one of many ways that regulates gene expression. The regulation of gene expression is dependent on the state of the gene. A gene cannot be transcribed when the promoter of the gene is wrapped around the nucleosome, forming a heterochromatin state; thus, the gene is inhibited from being transcribed. coversly Methylation of the histone protein causes the winding around the nucleosomes, transforming a euchromatin state into a heterochromatin state. Of course, SUV39H1 alone does not methtylate the histone proteins. SUV39H1 interacts with other proteins in order to efficiently methylate a histone protein (shown in Figure 1). | SUV39h1 is part of a class of enzymes that deals with the methyltransferase of histone proteins in nucleosomes. The methylation of histone proteins is an essential part of an area of genetics which deals with the modification of histone proteins called epigenomics. Epigenomics is the study of modifications of nucleosomes, which inhibit or express gene trancriscription without changing the underlining DNA sequence. Methylation of histone protein is one of many ways that regulates gene expression. The regulation of gene expression is dependent on the state of the gene. A gene cannot be transcribed when the promoter of the gene is wrapped around the nucleosome, forming a heterochromatin state; thus, the gene is inhibited from being transcribed. coversly Methylation of the histone protein causes the winding around the nucleosomes, transforming a euchromatin state into a heterochromatin state. Of course, SUV39H1 alone does not methtylate the histone proteins. SUV39H1 interacts with other proteins in order to efficiently methylate a histone protein (shown in Figure 1). | ||
[[Image:picture 1.jpg | | [[Image:picture 1.jpg | Frame |Figure 1 showing the methylation of the histone protein and the subsequent formation of heterochromatin]] | ||
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