2exg: Difference between revisions

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[[Image:2exg.gif|left|200px]]<br /><applet load="2exg" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2exg.gif|left|200px]]
caption="2exg" />
 
'''Making Protein-Protein Interactions Drugable: Discovery of Low-Molecular-Weight Ligands for the AF6 PDZ Domain'''<br />
{{Structure
|PDB= 2exg |SIZE=350|CAPTION= <scene name='initialview01'>2exg</scene>
|SITE=  
|LIGAND= <scene name='pdbligand=STF:(5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE'>STF</scene>
|ACTIVITY=
|GENE=
}}
 
'''Making Protein-Protein Interactions Drugable: Discovery of Low-Molecular-Weight Ligands for the AF6 PDZ Domain'''
 


==About this Structure==
==About this Structure==
2EXG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=STF:'>STF</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EXG OCA].  
2EXG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EXG OCA].  


==Reference==
==Reference==
Discovery of low-molecular-weight ligands for the AF6 PDZ domain., Joshi M, Vargas C, Boisguerin P, Diehl A, Krause G, Schmieder P, Moelling K, Hagen V, Schade M, Oschkinat H, Angew Chem Int Ed Engl. 2006 Jun 2;45(23):3790-5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16671149 16671149]
Discovery of low-molecular-weight ligands for the AF6 PDZ domain., Joshi M, Vargas C, Boisguerin P, Diehl A, Krause G, Schmieder P, Moelling K, Hagen V, Schade M, Oschkinat H, Angew Chem Int Ed Engl. 2006 Jun 2;45(23):3790-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16671149 16671149]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 17: Line 26:
[[Category: Vargas, C.]]
[[Category: Vargas, C.]]
[[Category: STF]]
[[Category: STF]]
[[Category: inhibitors of protein-protein interactions]]
[[Category: inhibitors of protein-protein interaction]]
[[Category: low-molecular-weight ligands]]
[[Category: low-molecular-weight ligand]]
[[Category: nmr screening]]
[[Category: nmr screening]]
[[Category: pdz domains]]
[[Category: pdz domain]]
[[Category: protein structure]]
[[Category: protein structure]]


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