4jsc: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_4jsc|  PDB=4jsc  |  SCENE=  }}
+===The 2.5A crystal structure of humanized Xenopus MDM2 with RO5316533 - a pyrrolidine MDM2 inhibitor===
+{{ABSTRACT_PUBMED_23808545}}
-The entry 4jsc is ON HOLD
+==Function==
+[[http://www.uniprot.org/uniprot/MDM2_XENLA MDM2_XENLA]] E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degration by the proteasome (By similarity).
-Authors: Janson, C.A., Lukacs, C., Graves, B.
+==About this Structure==
+[[4jsc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JSC OCA].
-Description: The 2.5A crystal structure of humanized Xenopus MDM2 with RO5316533 -a pyrrolidine MDM2 inhibitor
+==Reference==
+<ref group="xtra">PMID:023808545</ref><references group="xtra"/><references/>
+[[Category: Xenopus laevis]]
+[[Category: Graves, B.]]
+[[Category: Janson, C A.]]
+[[Category: Lukacs, C.]]
+[[Category: E3 ubiquitin ligase]]
+[[Category: Ligase-antagonist complex]]
+[[Category: Ligase-ligase inhibitor complex]]
+[[Category: Nucleus]]
+[[Category: P53]]
+[[Category: Pyrrolidine]]

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