4k0r: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_4k0r| PDB=4k0r | SCENE= }} | |||
===Crystal structure of mouse Cryptochrome 1=== | |||
{{ABSTRACT_PUBMED_23746849}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CRY1_MOUSE CRY1_MOUSE]] Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL.<ref>PMID:10428031</ref> <ref>PMID:16628007</ref> <ref>PMID:16478995</ref> | |||
==About this Structure== | |||
[[4k0r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K0R OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023746849</ref><references group="xtra"/><references/> | |||
[[Category: Mus musculus]] | |||
[[Category: Czarna, A.]] | |||
[[Category: Wolf, E.]] | |||
[[Category: Circadian clock protein]] | |||
[[Category: Phosphorylation]] | |||
[[Category: Rossmann fold]] | |||
