4k44: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_4k44|  PDB=4k44  |  SCENE=  }}
+===Auto-inhibition and phosphorylation-induced activation of PLC-gamma isozymes===
+{{ABSTRACT_PUBMED_23777354}}
-The entry 4k44 is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/PLCG1_RAT PLCG1_RAT]] Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration (By similarity).
-Authors: Hajicek, N., Sondek, J.
+==About this Structure==
+[[4k44]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K44 OCA].
-Description: Auto-inhibition and phosphorylation-induced activation of PLC-gamma isozymes
+==Reference==
+<ref group="xtra">PMID:023777354</ref><references group="xtra"/><references/>
+[[Category: Phosphoinositide phospholipase C]]
+[[Category: Rattus norvegicus]]
+[[Category: Hajicek, N.]]
+[[Category: Sondek, J.]]
+[[Category: Hydrolase]]
+[[Category: Plc-gamma1]]
+[[Category: Sh2 domain]]

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