4k5l: Difference between revisions
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{{STRUCTURE_4k5l| PDB=4k5l | SCENE= }} | |||
===Phosphonic Arginine Mimetics as Inhibitors of the M1 Aminopeptidases from Plasmodium falciparum=== | |||
{{ABSTRACT_PUBMED_23713488}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/AMP1_PLAFQ AMP1_PLAFQ]] Displays aminopeptidase activity with a broad substrate specificity. Preferentially hydrolyzes L-Lys-AMC but also shows strong activity against L-Ala-AMC, L-Arg-AMC and L-Leu-AMC.<ref>PMID:12166515</ref> <ref>PMID:19196988</ref> | |||
==About this Structure== | |||
[[4k5l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_fcb1/columbia Plasmodium falciparum fcb1/columbia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K5L OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023713488</ref><references group="xtra"/><references/> | |||
[[Category: Plasmodium falciparum fcb1/columbia]] | |||
[[Category: McGowan, S.]] | |||
[[Category: Hydrolase-hydrolase inhibitor complex]] | |||
[[Category: M1 alanyl-aminopeptidase]] | |||
[[Category: Protease]] | |||