4e9b: Difference between revisions

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~~{{STRUCTURE_4e9b| PDB=4e9b | SCENE= }}~~

==Structure of Peptide Deformylase form Helicobacter Pylori in complex with actinonin==

===Structure of Peptide Deformylase form Helicobacter Pylori in complex with actinonin===

== Structural highlights ==

==~~Function~~==

<table><tr><td colspan='2'>[[4e9b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E9B OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E9B FirstGlance].

[[~~http://www.uniprot.org/uniprot/Q672W7_HELPX Q672W7_HELPX~~]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).[~~HAMAP-Rule:MF_00163~~]

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4e9a|4e9a]]</td></tr>

==~~About this Structure~~==

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">def, def11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 Helicobacter pylori])</td></tr>

[[4e9b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E9B OCA].

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e9b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4e9b RCSB], [http://www.ebi.ac.uk/pdbsum/4e9b PDBsum]</td></tr>

</table>

__TOC__

</StructureSection>

[[Category: Helicobacter pylori]]

[[Category: Peptide deformylase]]

[[Category: Cui, K.]]

[[Category: Cui, K]]

[[Category: Huang, J.]]

[[Category: Huang, J]]

[[Category: Lu, W.]]

[[Category: Lu, W]]

[[Category: Zhu, L.]]

[[Category: Zhu, L]]

[[Category: Hydrolase-hydrolase inhibtior complex]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_4e9b|  PDB=4e9b  |  SCENE=  }}
+==Structure of Peptide Deformylase form Helicobacter Pylori in complex with actinonin==
-===Structure of Peptide Deformylase form Helicobacter Pylori in complex with actinonin===
+<StructureSection load='4e9b' size='340' side='right' caption='[[4e9b]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
+== Structural highlights ==
-==Function==
+<table><tr><td colspan='2'>[[4e9b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E9B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E9B FirstGlance]. <br>
-[[http://www.uniprot.org/uniprot/Q672W7_HELPX Q672W7_HELPX]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).[HAMAP-Rule:MF_00163]
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4e9a|4e9a]]</td></tr>
-==About this Structure==
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">def, def11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 Helicobacter pylori])</td></tr>
-[[4e9b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E9B OCA].
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e9b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4e9b RCSB], [http://www.ebi.ac.uk/pdbsum/4e9b PDBsum]</span></td></tr>
+</table>
+__TOC__
+</StructureSection>
 [[Category: Helicobacter pylori]]
 [[Category: Peptide deformylase]]
-[[Category: Cui, K.]]
+[[Category: Cui, K]]
-[[Category: Huang, J.]]
+[[Category: Huang, J]]
-[[Category: Lu, W.]]
+[[Category: Lu, W]]
-[[Category: Zhu, L.]]
+[[Category: Zhu, L]]
 [[Category: Hydrolase-hydrolase inhibtior complex]]