2f69: Difference between revisions

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[[Image:2f69.gif|left|200px]]<br /><applet load="2f69" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2f69.gif|left|200px]]
caption="2f69, resolution 1.30&Aring;" />
 
'''Ternary complex of SET7/9 bound to AdoHcy and a TAF10 peptide'''<br />
{{Structure
|PDB= 2f69 |SIZE=350|CAPTION= <scene name='initialview01'>2f69</scene>, resolution 1.30&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene> and <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43]
|GENE= SET7, KIAA1717 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Ternary complex of SET7/9 bound to AdoHcy and a TAF10 peptide'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2F69 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ACE:'>ACE</scene> and <scene name='pdbligand=SAH:'>SAH</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F69 OCA].  
2F69 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F69 OCA].  


==Reference==
==Reference==
Structural basis for the methylation site specificity of SET7/9., Couture JF, Collazo E, Hauk G, Trievel RC, Nat Struct Mol Biol. 2006 Feb;13(2):140-6. Epub 2006 Jan 15. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16415881 16415881]
Structural basis for the methylation site specificity of SET7/9., Couture JF, Collazo E, Hauk G, Trievel RC, Nat Struct Mol Biol. 2006 Feb;13(2):140-6. Epub 2006 Jan 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16415881 16415881]
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: set domain]]
[[Category: set domain]]


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