2f8i: Difference between revisions

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[[Image:2f8i.gif|left|200px]]<br /><applet load="2f8i" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2f8i.gif|left|200px]]
caption="2f8i, resolution 1.541&Aring;" />
 
'''Human transthyretin (TTR) complexed with Benzoxazole'''<br />
{{Structure
|PDB= 2f8i |SIZE=350|CAPTION= <scene name='initialview01'>2f8i</scene>, resolution 1.541&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=205:2-(2,6-DICHLOROPHENYL)-1,3-BENZOXAZOLE-6-CARBOXYLIC ACID'>205</scene>
|ACTIVITY=
|GENE= TTR, PALB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Human transthyretin (TTR) complexed with Benzoxazole'''
 


==Disease==
==Disease==
Line 7: Line 16:


==About this Structure==
==About this Structure==
2F8I is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=205:'>205</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F8I OCA].  
2F8I is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F8I OCA].  


==Reference==
==Reference==
Benzoxazoles as transthyretin amyloid fibril inhibitors: synthesis, evaluation, and mechanism of action., Razavi H, Palaninathan SK, Powers ET, Wiseman RL, Purkey HE, Mohamedmohaideen NN, Deechongkit S, Chiang KP, Dendle MT, Sacchettini JC, Kelly JW, Angew Chem Int Ed Engl. 2003 Jun 23;42(24):2758-61. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12820260 12820260]
Benzoxazoles as transthyretin amyloid fibril inhibitors: synthesis, evaluation, and mechanism of action., Razavi H, Palaninathan SK, Powers ET, Wiseman RL, Purkey HE, Mohamedmohaideen NN, Deechongkit S, Chiang KP, Dendle MT, Sacchettini JC, Kelly JW, Angew Chem Int Ed Engl. 2003 Jun 23;42(24):2758-61. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12820260 12820260]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: ttr; amyloid; transthyretin]]
[[Category: ttr; amyloid; transthyretin]]


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