3ney: Difference between revisions

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{{STRUCTURE_3ney|  PDB=3ney  |  SCENE=  }}
==Crystal structure of the kinase domain of MPP1/p55==
===Crystal structure of the kinase domain of MPP1/p55===
<StructureSection load='3ney' size='340' side='right' caption='[[3ney]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[3ney]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NEY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NEY FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/EM55_HUMAN EM55_HUMAN]] Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity).  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ney FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ney OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ney RCSB], [http://www.ebi.ac.uk/pdbsum/3ney PDBsum]</span></td></tr>
==About this Structure==
</table>
[[3ney]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NEY OCA].  
== Evolutionary Conservation ==
[[Category: Homo sapiens]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Arrowsmith, C H.]]
Check<jmol>
[[Category: Bochkarev, A.]]
  <jmolCheckbox>
[[Category: Bountra, C.]]
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ne/3ney_consurf.spt"</scriptWhenChecked>
[[Category: Edwards, A M.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Guan, X.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: MacKenzie, F.]]
  </jmolCheckbox>
[[Category: Park, H.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
[[Category: SGC, Structural Genomics Consortium.]]
<div style="clear:both"></div>
[[Category: Shen, Y.]]
__TOC__
[[Category: Tempel, W.]]
</StructureSection>
[[Category: Tong, Y.]]
[[Category: Arrowsmith, C H]]
[[Category: Weigelt, J.]]
[[Category: Bochkarev, A]]
[[Category: Zhong, N.]]
[[Category: Bountra, C]]
[[Category: Edwards, A M]]
[[Category: Guan, X]]
[[Category: MacKenzie, F]]
[[Category: Park, H]]
[[Category: Structural genomic]]
[[Category: Shen, Y]]
[[Category: Tempel, W]]
[[Category: Tong, Y]]
[[Category: Weigelt, J]]
[[Category: Zhong, N]]
[[Category: 55 kda erythrocyte membrane protein]]
[[Category: 55 kda erythrocyte membrane protein]]
[[Category: Membrane protein]]
[[Category: Membrane protein]]
[[Category: Sgc]]
[[Category: Sgc]]
[[Category: Structural genomics consortium]]