Lambda repressor: Difference between revisions

<StructureSection load='3bdn' size='350' side='right' caption='The spacefill model of the NTD highlights the interactions between the repressor and DNA. (PDB entry [[1lmb]])' scene='Bacteriophage_Lambda_Repressor_cI/Ntd_spacefill/1'>The NTD Lambda repressor consists of the first 92 amino acid residues of the protein and contains the <scene name='Bacteriophage_Lambda_Repressor_cI/Ntd_spacefill/1'>DNA-Binding Domain</scene> (Stayrook et. al, 2008) of the protein.  The secondary structure of the NTD is a compact conformation of six alpha-helices.  This secondary structure shows weak self-association, which is purported to aid in formation of the dimeric unit. The DNA-binding motif utilized by Lambda Repressor is a <scene name='Bacteriophage_Lambda_Repressor_cI/Hth_motif/1'>Helix-Turn-Helix</scene> (Beamer and Pabo, 1992).  The Helix-Turn-Helix motifs of two dimerized NTDs are illustrated in red to the right.</StructureSection>