4hwt: Difference between revisions

Revision as of 04:07, 20 September 2013

4hwt is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Teng M, Hilgers MT, Cunningham ML, Borchardt A, Locke JB, Abraham S, Haley G, Kwan BP, Hall C, Hough GW, Shaw KJ, Finn J. Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design. J Med Chem. 2013 Feb 28;56(4):1748-60. doi: 10.1021/jm301756m. Epub 2013 Feb 12. PMID:23362938 doi:10.1021/jm301756m

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-'''Unreleased structure'''
+{{STRUCTURE_4hwt|  PDB=4hwt  |  SCENE=  }}
+===Crystal structure of human Threonyl-tRNA synthetase bound to a novel inhibitor===
+{{ABSTRACT_PUBMED_23362938}}
-The entry 4hwt is ON HOLD  until Paper Publication
+==About this Structure==
+[[4hwt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HWT OCA].
-Authors: Hilgers, M.T.
+==Reference==
+<ref group="xtra">PMID:023362938</ref><references group="xtra"/><references/>
-Description: Crystal structure of human Threonyl-tRNA synthetase bound to a novel inhibitor
+[[Category: Homo sapiens]]
+[[Category: Threonine--tRNA ligase]]
+[[Category: Hilgers, M T.]]
+[[Category: Aminoacyl-trna synthetase]]
+[[Category: Ligase-ligase inhibitor complex]]
+[[Category: Protein-inhibitor complex]]