4itc: Difference between revisions
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{{STRUCTURE_4itc| PDB=4itc | SCENE= }} | |||
===Crystal Structure Analysis of the K1 Cleaved Adhesin domain of Lys-gingipain (Kgp) from Porphyromonas gingivalis W83=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/KGP83_PORGN KGP83_PORGN]] Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria (By similarity).[UniProtKB:B2RLK2] | |||
==About this Structure== | |||
[[4itc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Porphyromonas_gingivalis Porphyromonas gingivalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ITC OCA]. | |||
[[Category: Gingipain K]] | |||
[[Category: Porphyromonas gingivalis]] | |||
[[Category: Collyer, C A.]] | |||
[[Category: Ganuelas, L A.]] | |||
[[Category: Hunter, N.]] | |||
[[Category: Li, N.]] | |||
[[Category: Beta sandwich]] | |||
[[Category: Calcium binding]] | |||
[[Category: Cell invasion]] | |||
[[Category: Cleaved adhesin family]] | |||
[[Category: Cysteine protease]] | |||
[[Category: Hemagglutinin domain]] | |||
[[Category: Hydrolase]] | |||
[[Category: Lys-gingipain]] | |||
[[Category: Membrane surface]] | |||
Revision as of 08:18, 29 September 2013
Crystal Structure Analysis of the K1 Cleaved Adhesin domain of Lys-gingipain (Kgp) from Porphyromonas gingivalis W83
Function
[KGP83_PORGN] Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria (By similarity).[UniProtKB:B2RLK2]
About this Structure
4itc is a 1 chain structure with sequence from Porphyromonas gingivalis. Full crystallographic information is available from OCA.
