4jvl: Difference between revisions

Line 1:

~~'''Unreleased~~ structure~~'''~~

===Crystal structure of human estrogen sulfotransferase (SULT1E1) in complex with inactive cofactor PAP and estradiol (E2)===

~~The entry 4jvl is ON HOLD~~ ~~until Paper Publication~~

==Function==

[[http://www.uniprot.org/uniprot/ST1E1_HUMAN ST1E1_HUMAN]] Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol. Maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. Also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations; however, cortisol, testosterone and dopamine are not sulfated.<ref>PMID:11884392</ref>

~~Authors~~: ~~Gosavi, R~~.A.~~, Knudsen, G~~.~~A., Birnbaum, L~~.S.~~, Pedersen, L~~.C.

==About this Structure==

[[4jvl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JVL OCA].

~~Description~~: ~~Crystal structure of human estrogen~~ sulfotransferase ~~(SULT1E1) in complex with inactive cofactor PAP and estradiol (E2)~~

==Reference==

[[Category: Estrone sulfotransferase]]

[[Category: Homo sapiens]]

[[Category: Birnbaum, L S.]]

[[Category: Gosavi, R A.]]

[[Category: Knudsen, G A.]]

[[Category: Pedersen, L C.]]

[[Category: Cytosolic sulfotransferase]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4jvl|  PDB=4jvl  |  SCENE=  }}
+===Crystal structure of human estrogen sulfotransferase (SULT1E1) in complex with inactive cofactor PAP and estradiol (E2)===
+{{ABSTRACT_PUBMED_23959441}}
-The entry 4jvl is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/ST1E1_HUMAN ST1E1_HUMAN]] Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol. Maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. Also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations; however, cortisol, testosterone and dopamine are not sulfated.<ref>PMID:11884392</ref>
-Authors: Gosavi, R.A., Knudsen, G.A., Birnbaum, L.S., Pedersen, L.C.
+==About this Structure==
+[[4jvl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JVL OCA].
-Description: Crystal structure of human estrogen sulfotransferase (SULT1E1) in complex with inactive cofactor PAP and estradiol (E2)
+==Reference==
+<ref group="xtra">PMID:023959441</ref><references group="xtra"/><references/>
+[[Category: Estrone sulfotransferase]]
+[[Category: Homo sapiens]]
+[[Category: Birnbaum, L S.]]
+[[Category: Gosavi, R A.]]
+[[Category: Knudsen, G A.]]
+[[Category: Pedersen, L C.]]
+[[Category: Cytosolic sulfotransferase]]
+[[Category: Transferase]]