4k6l: Difference between revisions
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{{STRUCTURE_4k6l| PDB=4k6l | SCENE= }} | |||
===Structure of Typhoid Toxin=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CDTB_SALTI CDTB_SALTI]] Produces a CDT (cytolethal distending toxin) activity, which causes DNA damage in intoxicated cells. This damage induces G2/M cell cycle arrest, chromatin fragmentation, cell distention and nucleus enlargement. | |||
==About this Structure== | |||
[[4k6l]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhi Salmonella enterica subsp. enterica serovar typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6L OCA]. | |||
[[Category: Salmonella enterica subsp. enterica serovar typhi]] | |||
[[Category: Galan,J.]] | |||
[[Category: Gao,X.]] | |||
[[Category: Song,J.]] | |||
[[Category: Bacterial toxin]] | |||
[[Category: Complex]] | |||
[[Category: Sugar]] | |||
[[Category: Toxin]] | |||
Revision as of 05:04, 18 July 2013
Structure of Typhoid Toxin
Function
[CDTB_SALTI] Produces a CDT (cytolethal distending toxin) activity, which causes DNA damage in intoxicated cells. This damage induces G2/M cell cycle arrest, chromatin fragmentation, cell distention and nucleus enlargement.
About this Structure
4k6l is a 7 chain structure with sequence from Salmonella enterica subsp. enterica serovar typhi. Full crystallographic information is available from OCA.
