4kax: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4kax|  PDB=4kax  |  SCENE=  }}
===Crystal structure of the Grp1 PH domain in complex with Arf6-GTP===


The entry 4kax is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/ARF6_HUMAN ARF6_HUMAN]] GTP-binding protein involved in protein trafficking; regulates endocytic recycling and cytoskeleton remodeling. May modulate vesicle budding and uncoating within the Golgi apparatus. Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in the regulation of dendritic spine development (By similarity). Contributes to the regulation of dendritic branching and filopodia extension.<ref>PMID:7589240</ref> <ref>PMID:14978216</ref> <ref>PMID:11266366</ref>  [[http://www.uniprot.org/uniprot/CYH3_HUMAN CYH3_HUMAN]] Promotes guanine-nucleotide exchange on ARF1. Promotes the activation of ARF through replacement of GDP with GTP.


Authors: Lambright, D.G., Malaby, A.W., van den Berg, B.
==About this Structure==
[[4kax]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KAX OCA].  


Description: Crystal structure of the Grp1 PH domain in complex with Arf6-GTP
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Berg, B van den.]]
[[Category: Lambright, D G.]]
[[Category: Malaby, A W.]]
[[Category: Ph domain]]
[[Category: Phosphoinositide]]
[[Category: Protein binding-signaling protein complex]]