2fhx: Difference between revisions

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[[Image:2fhx.gif|left|200px]]<br /><applet load="2fhx" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2fhx.gif|left|200px]]
caption="2fhx, resolution 1.900&Aring;" />
 
'''Pseudomonas aeruginosa SPM-1 metallo-beta-lactamase'''<br />
{{Structure
|PDB= 2fhx |SIZE=350|CAPTION= <scene name='initialview01'>2fhx</scene>, resolution 1.900&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6]
|GENE= blaSPM-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])
}}
 
'''Pseudomonas aeruginosa SPM-1 metallo-beta-lactamase'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2FHX is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=AZI:'>AZI</scene>, <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FHX OCA].  
2FHX is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FHX OCA].  


==Reference==
==Reference==
Crystal structure of Pseudomonas aeruginosa SPM-1 provides insights into variable zinc affinity of metallo-beta-lactamases., Murphy TA, Catto LE, Halford SE, Hadfield AT, Minor W, Walsh TR, Spencer J, J Mol Biol. 2006 Mar 31;357(3):890-903. Epub 2006 Jan 23. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16460758 16460758]
Crystal structure of Pseudomonas aeruginosa SPM-1 provides insights into variable zinc affinity of metallo-beta-lactamases., Murphy TA, Catto LE, Halford SE, Hadfield AT, Minor W, Walsh TR, Spencer J, J Mol Biol. 2006 Mar 31;357(3):890-903. Epub 2006 Jan 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16460758 16460758]
[[Category: Beta-lactamase]]
[[Category: Beta-lactamase]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: structure]]
[[Category: structure]]


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