4iox: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
[[4iox]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_1 Human herpesvirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IOX OCA]. | [[4iox]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_1 Human herpesvirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IOX OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:023596306</ref><references group="xtra"/><references/> | |||
[[Category: Human herpesvirus 1]] | [[Category: Human herpesvirus 1]] | ||
[[Category: Kamau, Y.]] | [[Category: Kamau, Y.]] | ||
Revision as of 07:51, 19 June 2013
The structure of the herpes simplex virus DNA-packaging motor pUL15 C-terminal nuclease domain provides insights into cleavage of concatemeric viral genome precursors
Template:ABSTRACT PUBMED 23596306
Function
[TRM3_HHV11] Component of the molecular motor that translocates genomic DNA in empty capsid during DNA packaging. Heterodimerizes with small terminase protein to be docked on capsid portal protein. The latter forms a ring in which genomic DNA in translocated into the capsid. May have or induce an endonuclease activity to cleave the genome concatemer after encapsidation.
About this Structure
4iox is a 4 chain structure with sequence from Human herpesvirus 1. Full crystallographic information is available from OCA.
Reference
- Sigamani SS, Zhao H, Kamau YN, Baines JD, Tang L. The structure of the herpes simplex virus DNA-packaging terminase pUL15 nuclease domain suggests an evolutionary lineage among eukaryotic and prokaryotic viruses. J Virol. 2013 Apr 17. PMID:23596306 doi:10.1128/JVI.00311-13
