2fil: Difference between revisions

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[[Image:2fil.gif|left|200px]]<br /><applet load="2fil" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2fil.gif|left|200px]]
caption="2fil, resolution 1.69&Aring;" />
 
'''Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-faT-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and 2'-Fluoroarabino-Thymidine (faT)'''<br />
{{Structure
|PDB= 2fil |SIZE=350|CAPTION= <scene name='initialview01'>2fil</scene>, resolution 1.69&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NCO:COBALT HEXAMMINE ION'>NCO</scene>
|ACTIVITY=
|GENE=
}}
 
'''Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-faT-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and 2'-Fluoroarabino-Thymidine (faT)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2FIL is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=NCO:'>NCO</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIL OCA].  
2FIL is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIL OCA].  


==Reference==
==Reference==
2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H., Li F, Sarkhel S, Wilds CJ, Wawrzak Z, Prakash TP, Manoharan M, Egli M, Biochemistry. 2006 Apr 4;45(13):4141-52. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16566588 16566588]
2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H., Li F, Sarkhel S, Wilds CJ, Wawrzak Z, Prakash TP, Manoharan M, Egli M, Biochemistry. 2006 Apr 4;45(13):4141-52. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16566588 16566588]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Egli, M.]]
[[Category: Egli, M.]]
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[[Category: 2'-fluoroarabino acid]]
[[Category: 2'-fluoroarabino acid]]
[[Category: a-form dna]]
[[Category: a-form dna]]
[[Category: sugar modifications]]
[[Category: sugar modification]]


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