2fnm: Difference between revisions

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[[Image:2fnm.gif|left|200px]]<br /><applet load="2fnm" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2fnm.gif|left|200px]]
caption="2fnm, resolution 1.8&Aring;" />
 
'''Activation of human carbonic anhdyrase II by exogenous proton donors'''<br />
{{Structure
|PDB= 2fnm |SIZE=350|CAPTION= <scene name='initialview01'>2fnm</scene>, resolution 1.8&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC ION'>ZN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1]
|GENE= HCA II, CA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Activation of human carbonic anhdyrase II by exogenous proton donors'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2FNM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FNM OCA].  
2FNM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FNM OCA].  


==Reference==
==Reference==
Location of binding sites in small molecule rescue of human carbonic anhydrase II., Bhatt D, Fisher SZ, Tu C, McKenna R, Silverman DN, Biophys J. 2007 Jan 15;92(2):562-70. Epub 2006 Oct 27. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17071654 17071654]
Location of binding sites in small molecule rescue of human carbonic anhydrase II., Bhatt D, Fisher SZ, Tu C, McKenna R, Silverman DN, Biophys J. 2007 Jan 15;92(2):562-70. Epub 2006 Oct 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17071654 17071654]
[[Category: Carbonate dehydratase]]
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: proton transfer]]
[[Category: proton transfer]]


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