2fo0: Difference between revisions

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[[Image:2fo0.gif|left|200px]]<br /><applet load="2fo0" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2fo0.gif|left|200px]]
caption="2fo0, resolution 2.27&Aring;" />
 
'''Organization of the SH3-SH2 Unit in Active and Inactive Forms of the c-Abl Tyrosine Kinase'''<br />
{{Structure
|PDB= 2fo0 |SIZE=350|CAPTION= <scene name='initialview01'>2fo0</scene>, resolution 2.27&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene>, <scene name='pdbligand=P16:6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE'>P16</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2]
|GENE= c-Abl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Organization of the SH3-SH2 Unit in Active and Inactive Forms of the c-Abl Tyrosine Kinase'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2FO0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MYR:'>MYR</scene>, <scene name='pdbligand=P16:'>P16</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FO0 OCA].  
2FO0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FO0 OCA].  


==Reference==
==Reference==
Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase., Nagar B, Hantschel O, Seeliger M, Davies JM, Weis WI, Superti-Furga G, Kuriyan J, Mol Cell. 2006 Mar 17;21(6):787-98. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16543148 16543148]
Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase., Nagar B, Hantschel O, Seeliger M, Davies JM, Weis WI, Superti-Furga G, Kuriyan J, Mol Cell. 2006 Mar 17;21(6):787-98. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16543148 16543148]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: sh3-sh2 clamp]]
[[Category: sh3-sh2 clamp]]


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