3otd: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3otd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3otd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycta Mycta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OTD OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:021059936</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:021059936</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: Mycta]] | ||
[[Category: Doublie, S.]] | [[Category: Doublie, S.]] | ||
[[Category: Eckenroth, B E.]] | [[Category: Eckenroth, B E.]] | ||
Revision as of 05:23, 9 April 2014
Crystal structure of human tRNAHis guanylyltransferase (Thg1)- NaI derivative
Template:ABSTRACT PUBMED 21059936
Function
[THG1_HUMAN] Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.[1]
About this Structure
3otd is a 2 chain structure with sequence from Mycta. Full crystallographic information is available from OCA.
Reference
- Hyde SJ, Eckenroth BE, Smith BA, Eberley WA, Heintz NH, Jackman JE, Doublie S. tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases. Proc Natl Acad Sci U S A. 2010 Nov 8. PMID:21059936 doi:10.1073/pnas.1010436107
- ↑ Hyde SJ, Eckenroth BE, Smith BA, Eberley WA, Heintz NH, Jackman JE, Doublie S. tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases. Proc Natl Acad Sci U S A. 2010 Nov 8. PMID:21059936 doi:10.1073/pnas.1010436107
