2fp7: Difference between revisions

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[[Image:2fp7.gif|left|200px]]<br /><applet load="2fp7" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2fp7.gif|left|200px]]
caption="2fp7, resolution 1.68&Aring;" />
 
'''West Nile Virus NS2B/NS3protease in complex with Bz-Nle-Lys-Arg-Arg-H'''<br />
{{Structure
|PDB= 2fp7 |SIZE=350|CAPTION= <scene name='initialview01'>2fp7</scene>, resolution 1.68&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NDL:N-BENZOYL-L-NORLEUCYL-L-LYSYL-L-ARGINYL-L-ARGININE'>NDL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Flavivirin Flavivirin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.91 3.4.21.91]
|GENE=
}}
 
'''West Nile Virus NS2B/NS3protease in complex with Bz-Nle-Lys-Arg-Arg-H'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2FP7 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/West_nile_virus West nile virus] with <scene name='pdbligand=NDL:'>NDL</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Flavivirin Flavivirin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.91 3.4.21.91] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FP7 OCA].  
2FP7 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/West_nile_virus West nile virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FP7 OCA].  


==Reference==
==Reference==
Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus., Erbel P, Schiering N, D'Arcy A, Renatus M, Kroemer M, Lim SP, Yin Z, Keller TH, Vasudevan SG, Hommel U, Nat Struct Mol Biol. 2006 Apr;13(4):372-3. Epub 2006 Mar 12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16532006 16532006]
Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus., Erbel P, Schiering N, D'Arcy A, Renatus M, Kroemer M, Lim SP, Yin Z, Keller TH, Vasudevan SG, Hommel U, Nat Struct Mol Biol. 2006 Apr;13(4):372-3. Epub 2006 Mar 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16532006 16532006]
[[Category: Flavivirin]]
[[Category: Flavivirin]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: substrate-based inhibitor]]
[[Category: substrate-based inhibitor]]


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