2fr0: Difference between revisions

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[[Image:2fr0.gif|left|200px]]<br /><applet load="2fr0" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2fr0.gif|left|200px]]
caption="2fr0, resolution 1.81&Aring;" />
 
'''The first ketoreductase of the erythromycin synthase (crystal form 1)'''<br />
{{Structure
|PDB= 2fr0 |SIZE=350|CAPTION= <scene name='initialview01'>2fr0</scene>, resolution 1.81&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE'>NDP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/3-oxoacyl-[acyl-carrier-protein]_reductase 3-oxoacyl-[acyl-carrier-protein] reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.100 1.1.1.100]
|GENE= eryAI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1836 Saccharopolyspora erythraea])
}}
 
'''The first ketoreductase of the erythromycin synthase (crystal form 1)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2FR0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharopolyspora_erythraea Saccharopolyspora erythraea] with <scene name='pdbligand=NDP:'>NDP</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/3-oxoacyl-[acyl-carrier-protein]_reductase 3-oxoacyl-[acyl-carrier-protein] reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.100 1.1.1.100] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FR0 OCA].  
2FR0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharopolyspora_erythraea Saccharopolyspora erythraea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FR0 OCA].  


==Reference==
==Reference==
The structure of a ketoreductase determines the organization of the beta-carbon processing enzymes of modular polyketide synthases., Keatinge-Clay AT, Stroud RM, Structure. 2006 Apr;14(4):737-48. Epub 2006 Mar 23. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16564177 16564177]
The structure of a ketoreductase determines the organization of the beta-carbon processing enzymes of modular polyketide synthases., Keatinge-Clay AT, Stroud RM, Structure. 2006 Apr;14(4):737-48. Epub 2006 Mar 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16564177 16564177]
[[Category: 3-oxoacyl-[acyl-carrier-protein] reductase]]
[[Category: 3-oxoacyl-[acyl-carrier-protein] reductase]]
[[Category: Saccharopolyspora erythraea]]
[[Category: Saccharopolyspora erythraea]]
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[[Category: short chain dehydrogenase/reductase]]
[[Category: short chain dehydrogenase/reductase]]


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