2fr0: Difference between revisions
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[[Image:2fr0.gif|left|200px]] | [[Image:2fr0.gif|left|200px]] | ||
'''The first ketoreductase of the erythromycin synthase (crystal form 1)''' | {{Structure | ||
|PDB= 2fr0 |SIZE=350|CAPTION= <scene name='initialview01'>2fr0</scene>, resolution 1.81Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE'>NDP</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/3-oxoacyl-[acyl-carrier-protein]_reductase 3-oxoacyl-[acyl-carrier-protein] reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.100 1.1.1.100] | |||
|GENE= eryAI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1836 Saccharopolyspora erythraea]) | |||
}} | |||
'''The first ketoreductase of the erythromycin synthase (crystal form 1)''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2FR0 is a [ | 2FR0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharopolyspora_erythraea Saccharopolyspora erythraea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FR0 OCA]. | ||
==Reference== | ==Reference== | ||
The structure of a ketoreductase determines the organization of the beta-carbon processing enzymes of modular polyketide synthases., Keatinge-Clay AT, Stroud RM, Structure. 2006 Apr;14(4):737-48. Epub 2006 Mar 23. PMID:[http:// | The structure of a ketoreductase determines the organization of the beta-carbon processing enzymes of modular polyketide synthases., Keatinge-Clay AT, Stroud RM, Structure. 2006 Apr;14(4):737-48. Epub 2006 Mar 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16564177 16564177] | ||
[[Category: 3-oxoacyl-[acyl-carrier-protein] reductase]] | [[Category: 3-oxoacyl-[acyl-carrier-protein] reductase]] | ||
[[Category: Saccharopolyspora erythraea]] | [[Category: Saccharopolyspora erythraea]] | ||
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[[Category: short chain dehydrogenase/reductase]] | [[Category: short chain dehydrogenase/reductase]] | ||
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