Complement Regulator-Acquiring Surface Protein: Difference between revisions
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== '''Function''' == | == '''Function''' == | ||
Bb CRASP-1 can be found on the outer layer of the Lyme disease spirochete and it is essential for the infiltration of the spirochete into the host (Bykowski 2007). BbCRASP-1 provides resistance for the spirochete against the hosts immune system. This is accomplished because BbCRASP-1 | |||
layer of the Lyme disease spirochete and it is essential for the infiltration of the spirochete into the host (Bykowski 2007). BbCRASP-1 provides resistance for the spirochete against the hosts immune system. This is accomplished because BbCRASP-1 | |||
has an affinity for factor H and therefore, the spirochete is covered in factor H and | has an affinity for factor H and therefore, the spirochete is covered in factor H and | ||
able to infiltrate the host without being recognized (Bykowski 2007). Factor H is a | able to infiltrate the host without being recognized (Bykowski 2007). Factor H is a | ||