2fyb: Difference between revisions

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[[Image:2fyb.gif|left|200px]]<br /><applet load="2fyb" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2fyb.gif|left|200px]]
caption="2fyb, resolution 1.90&Aring;" />
 
'''Crystal structure of the catalytic domain of the human beta1,4-galactosyltransferase mutant M339H in complex with Mn and UDP-galactose in open conformation'''<br />
{{Structure
|PDB= 2fyb |SIZE=350|CAPTION= <scene name='initialview01'>2fyb</scene>, resolution 1.90&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> and <scene name='pdbligand=UDP:URIDINE-5'-DIPHOSPHATE'>UDP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/N-acetyllactosamine_synthase N-acetyllactosamine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.90 2.4.1.90]
|GENE= B4GALT1, GGTB2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of the catalytic domain of the human beta1,4-galactosyltransferase mutant M339H in complex with Mn and UDP-galactose in open conformation'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2FYB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MN:'>MN</scene> and <scene name='pdbligand=UDP:'>UDP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/N-acetyllactosamine_synthase N-acetyllactosamine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.90 2.4.1.90] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FYB OCA].  
2FYB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FYB OCA].  


==Reference==
==Reference==
Structural snapshots of beta-1,4-galactosyltransferase-I along the kinetic pathway., Ramakrishnan B, Ramasamy V, Qasba PK, J Mol Biol. 2006 Apr 14;357(5):1619-33. Epub 2006 Feb 9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16497331 16497331]
Structural snapshots of beta-1,4-galactosyltransferase-I along the kinetic pathway., Ramakrishnan B, Ramasamy V, Qasba PK, J Mol Biol. 2006 Apr 14;357(5):1619-33. Epub 2006 Feb 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16497331 16497331]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: N-acetyllactosamine synthase]]
[[Category: N-acetyllactosamine synthase]]
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[[Category: open conformation]]
[[Category: open conformation]]


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