|
|
| Line 1: |
Line 1: |
| {{STRUCTURE_4iw5| PDB=4iw5 | SCENE= }}
| | #REDIRECT [[4knz]] This PDB entry is obsolete and replaced by 4knz |
| ===Thymidylate synthase ternary complex with dUMP and CB3717===
| |
| {{ABSTRACT_PUBMED_23611499}}
| |
| | |
| ==Function==
| |
| [[http://www.uniprot.org/uniprot/TYSY_ECOLI TYSY_ECOLI]] Provides the sole de novo source of dTMP for DNA biosynthesis. This protein also binds to its mRNA thus repressing its own translation. | |
| | |
| ==About this Structure==
| |
| [[4iw5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2g8o 2g8o]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IW5 OCA].
| |
| | |
| ==Reference==
| |
| <ref group="xtra">PMID:016768437</ref><references group="xtra"/><references/>
| |
| [[Category: Escherichia coli k-12]]
| |
| [[Category: Thymidylate synthase]]
| |
| [[Category: Finer-Moore, J.]]
| |
| [[Category: Lee, T T.]]
| |
| [[Category: Newby, Z.]]
| |
| [[Category: Stroud, R M.]]
| |
| [[Category: Alpha/beta protein]]
| |
| [[Category: Antifolate]]
| |
| [[Category: Methylenetetrahydrofolate]]
| |
| [[Category: Methyltransferase]]
| |
| [[Category: Transferase]]
| |
This PDB entry is obsolete and replaced by 4knz
