4bl6: Difference between revisions
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{{STRUCTURE_4bl6| PDB=4bl6 | SCENE= }} | |||
===Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to co-ordinate recruitment of cargos to dynein=== | |||
{{ABSTRACT_PUBMED_23723415}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/BICD_DROME BICD_DROME]] This protein is essential for differentiation. It may play a role in localizing of Nanos (a maternal determinant) activity in oocytes. BicD mutations cause Nanos mislocalization and thus bicaudal development. | |||
==About this Structure== | |||
[[4bl6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BL6 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023723415</ref><references group="xtra"/><references/> | |||
[[Category: Drosophila melanogaster]] | |||
[[Category: Bullock, S L.]] | |||
[[Category: Holding, A N.]] | |||
[[Category: Johnson, C M.]] | |||
[[Category: Liu, Y.]] | |||
[[Category: Lukavsky, P J.]] | |||
[[Category: Salter, H K.]] | |||
[[Category: Stephens, E.]] | |||
[[Category: Walshaw, J.]] | |||
[[Category: Cargo binding]] | |||
[[Category: Protein transport]] | |||
Revision as of 13:46, 19 June 2013
Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to co-ordinate recruitment of cargos to dynein
Template:ABSTRACT PUBMED 23723415
Function
[BICD_DROME] This protein is essential for differentiation. It may play a role in localizing of Nanos (a maternal determinant) activity in oocytes. BicD mutations cause Nanos mislocalization and thus bicaudal development.
About this Structure
4bl6 is a 4 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.
Reference
- Liu Y, Salter HK, Holding AN, Johnson CM, Stephens E, Lukavsky PJ, Walshaw J, Bullock SL. Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to coordinate recruitment of cargos to dynein. Genes Dev. 2013 Jun 1;27(11):1233-46. doi: 10.1101/gad.212381.112. Epub 2013 May , 30. PMID:23723415 doi:10.1101/gad.212381.112
