4k5a: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4k5a|  PDB=4k5a  |  SCENE=  }}
===Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W===


The entry 4k5a is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/B2CL2_BOVIN B2CL2_BOVIN]] Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX (By similarity).


Authors: Schilling, J., Schoeppe, J., Sauer, E., Plueckthun, A.
==About this Structure==
 
[[4k5a]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K5A OCA].  
Description: First crystal structure of anti-apoptotic BCL-W in its closed conformation
[[Category: Plueckthun, A.]]
[[Category: Sauer, E.]]
[[Category: Schilling, J.]]
[[Category: Schoeppe, J.]]
[[Category: Anti-apoptotic bcl-2 family]]
[[Category: Apoptosis]]
[[Category: Bcl-w]]
[[Category: Crystal structure]]
[[Category: Darpin]]
[[Category: Ligand binding-competent conformation]]